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Aksolotl kol rejenerasyonu alanında mikrobiyota ve transkriptom verisinin madenciliği vasıtasıyla yeni aday biyobelirteçlerin keşfi
Öğdür, Muhammed Mustafa (İstanbul Medipol Üniversitesi, Fen Bilimleri Enstitüsü, 2022)Son zamanlarda transkriptom ve mikrobiyota profillerini daha etkili ortaya çıkarabilen Yeni Nesil Dizilimi teknolojisinin yaygınlaşması rejenerasyonda mikrobiyotanın ve transkriptomun rolüne dikkat çekmektedirler. İntegratif ... -
The impact of COVID-19 on patients with chronic obstructive pulmonary disease
Bener, Abdulbari; Kök, Kıvanç; Naser, Abdulrahman; Barışık, Cem Cahit; Nurkalem, Zekeriya (Edizioni Minerva Medica, 2023)BACKGROUND: The aim of this study was to evaluate the risk of serious adverse outcomes in patients with chronic obstructive pulmonary disease (COPD) related to COVID-19 by stratifying the comorbidity status.METHODS: This ... -
Investigation of the candidate tumor suppressor gene CTCF using multi-omics data mining
Dursun, Esra (İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2021)CCCTC binding factor (CTCF) is a vertebrate, 11-zinc-finger protein. This ubiquitously expressed multifunctional transcription factor can bind to a myriad of target sites in the genome. It is involved, among others, in ... -
A longitudinal study of the association between depression, anxiety and stress symptoms of university students in Serbia with excessive social media use before and during COVID-19 pandemic
Visnjic, Aleksandar; Kök, Kıvanç; Višnjić, Jovana; Jovanović, Tamara; Marković, Roberta (Frontiers Media SA, 2023)Background: Besides the well known good side of social media, it cannot be denied some of its negative effects. This two-phase study aimed to find out whether the usage of social media during the COVID-19 pandemic showed ... -
A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
Gozel, Hilal Eren; Kök, Kıvanç; Özlen, Fatma; İşler, Cihan; Pençe, Sadrettin (Nature Research, 2021)Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ...